Since the start MIL-STD-1553, has found many applications. Note 2 to the same level, all references to the aircraft or in the air, thus removed, which limits its use. In spite of all the programs are usually here a long discussion, the following provides an overview of its use. Although the model is a constellation of satellites and spacecraft loads (still in use aboard the ISS is used), military applications and wider.

This is an important transportation, air tankers and bombers, tactical fighters and helicopters used. It is also involved in missile systems and used in some cases the primary interface with the machine! and arugula. The Navy has asked lautobus, and surface and subsurface vessels. Tear country and helicopters, tanks and 1553 cases of mortars. Commercial applications are standard, including the subway, which is used, for example, Bay Area Rapid Transit (Bart), and production. MIL-STD-1553B also adopt and implement NATO and other foreign governments. The United Kingdom has launched DEF STAN 00-18 (Part 2) and NATO STANAG 3838 AVS, and both versions of MIL-STD-1553B data. Widespread acceptance and MIL-STD-1553B also contributed to the standardization efforts of others. MIL-STD-1773 is a fiberglass version of 1553B. And MIL-STD-1760, Airplane! / Commercial Interconnect located 1553B.